University of Maryland

College of Agriculture & Natural Resources

Department of Veterinary Medicine

Xiaoping Zhu

D.V.M., Ph.D. Professor

E-mail: xzhu1@umd.edu
Phone: 301 314-6814
Fax: 301-314-6855
Lab: 301-314-5626

 

Education and Professional Experience

  • 2008 Associate Professor, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland
  • 2003 Assistant Professor, Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland, College Park, Maryland
  • 2000 Instructor in Medicine (Junior Faculty), Harvard Medical School and Brigham & Women's Hospital
  • 1997 Postdoctoral, Immunology, Harvard Medical School and Brigham & Women's Hospital
  • 1997 PhD, Virology, University of Wisconsin-Madison, Madison, Wisconsin
  • 1989 Lecturer, College of Veterinary Medicine, China Agricultural University, Beijing, China
  • 1987 Assistant Lecturer, College of Veterinary Medicine, China Agricultural University, Beijing, China
  • 1987 MS, Pathology, China Agricultural University, Beijing, China
  • 1984 DVM, Veterinary Medicine, Ningxia University, Yinchuan, China


Current Research Topics

  • Identification of new mechanisms of immune regulation on mucosal infections and inflammations at molecular and cellular immunology level;
  • How the mucosal immune system distinguishes pathogenic from non-pathogenic microbes and how pathogens evade innate and adaptive immunity
  • Harnessing innate and adaptive immunity for mucosal vaccine development and immunotherapy.


Publications

  • Liu X, Ye L, Christianson G, Yang J, Roopenian DC, Zhu X. NF-kappa B signaling regulates the functional expression of MHC class I-related human neonatal Fc receptor via intronic binding sequences. J. Immunol. 2007; 179:2999-3011.Editorial Commentary: The Importance of Introns in FcRn.
  • Ye L, Zeng R, Bai Y, Roopenian DC, Zhu X. Efficient mucosal vaccination mediated by the neonatal Fc receptor. Nature Biotechnol. 2011; 29:158-163. Editorial Commentary: FcRn-Escorted Mucosal Vaccine. News And Views: McGhee JR. A Mucosal Gateway For Vaccines. Nature Biotechnol. 2011; 29:136-138. *Evaluated by Faculty of 1000 Biology.
  • Palaniyandi S, Tomei E, Li Z, Conrad D, Zhu X. CD23-mediated transcytosis of IgE and immune complexes across the polarized human respiratory epithelial cells. J. Immunol., 2011; 186:3484-3496. Editorial Commentary: Aiding Allergy.
  • Li Z, Palaniyandi S, Zeng R, Tuo W, Roopenian DC, Zhu X. ­­Transfer of immunoglobulin G in the female genital tract by a MHC class I-related neonatal Fc receptor confers protective immunity to vaginal infections.Proc. Natl. Acad. Sci. (USA). 2011;In press. Editorial Commentary: Placental immune protein helps fight vaginal infection. Press Tip:Placental protein helps prevent STDs in mice...
  • Liu X, Lu L, Yang Z, Palaniyandi S, Zeng R, Gao L, Mosser DM, Roopenian DC, Zhu X. FcRn-mediated presentation of immune-complexed antigen is associated with the endosomal and phagosomal acidification and antigen stability in macrophages and dendritic cells.J. Immunol., 2011, 186:000-000. In press.
Maintained by the IET Department of the College of Agriculture and Natural Resources. © 2014.