College of Agriculture & Natural Resources
Department of Veterinary Medicine

Newcastle Disease Virus - Paramyxoviruses

Newcastle disease is a contagious bird disease affecting many domestic and wild avian species; it is transmissible to humans. Newcastle has a negative-sense, single-stranded genome which codes for a RNA-directed RNA polymerase, hemagglutinin-neuraminidase protein, fusion protein, matrix protein, phosphoprotein and nucleoprotein in the 5' to 3' direction.

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