Dr. Siba K. Samal

Siba Samal, Professor

Paramyxovires Pathogenesis and Vaccine Development

Education

1976: Orissa University of Agriculture and Technology, India, Veterinary Medicine, B.V.Sc. & A.H.

1978: Indian Veterinary Research Institute, Veterinary Virology, M.V.Sc. 

1981: Texas A & M University, Veterinary Virology, M.S. 

1985: Texas A & M University (Co-op Program with Baylor College of Medicine), Molecular Virology, Ph.D. 

1985 - 1986: Baylor College of Medicine, Molecular Virology, Postdoctoral

1986 - 1988: Plum Island Animal Disease Center, Molecular Virology, Postdoctoral

1988: Diplomate, American College of Veterinary Microbiologist

Professional Experience

1998 - present: Professor Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland

2002 - 2017: Associate Dean and Department Chair Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland

2001: Interim Associate Dean and Interim Department Chair Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland

1994 - 2001: Special Volunteer Laboratory of Infectious Diseases, National Institute of Health, Bethesda, Maryland

1994: Visiting Scientist (on sabbatical leave) Laboratory of Infectious Diseases, National Institute of Health, Bethesda, Maryland. Advisor: Dr. Peter L. Collins

1993 - 1998: Associate Professor Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland

1993 - 1998: Assistant Professor Virginia-Maryland Regional College of Veterinary Medicine, University of Maryland 

1986 - 1988: Postdoctoral Fellow Molecular Biology Section, Plum Island Animal Disease Center, U.S.D.A. Advisor: Dr. Marvin J. Grubman 

1985 - 1986: Postdoctoral Fellow Department of Virology, Baylor College of Medicine. Advisor: Dr. R. Frank Ramig 

Current Research Topics

Identification of molecular determinants of paramyxovires virulence

Identification of the mechanisms of paramyxovires pathogenesis

Molecular characterization of new and emerging avian paramyxoviruses

Engineering avian paramyxoviruses as vaccine vectors against animal and human disease

Development of novel avian paramyxovirus using vectors reverse genetics system

Avian paramyxoviruses as oncolytic agents

Books Edited

The Biology of Paramyxoviruses, Caister Academic Press, 2011.

Avian Virology: Current Research and Future Trends, Caister Academic Press, 2019

Viral Vectors in Veterinary Vaccine Development. A Textbook. Co-edited by Vanniasinkam, Tikoo, and Samal. Springer Nature, in press, 2019.

Editorship

Section Editor, veterinary RNA viruses, Virology Journal

Academic Editor, Plos One

Editorial Board Member, Virus Research

Editorial Board Member, Virus Diseases

Guest Editor, Newcastle Disease Vaccines: Current Research and Future Trends, Pathogens, 2019

Publications (more than 170 publications)

Viktorova EGKhattar SKKouiavskaia DLaassri MZagorodnyaya TDragunsky ESamal SChumakov KBelov GA. Newcastle Disease Virus-Based Vectored Vaccine against Poliomyelitis. J Virol. 92(17), 2018 Aug 16.

Michelle MeyerAsuka YoshidaPalaniappan RamanathanErica Ollmann SaphirePeter L. CollinsJames E. Crowe, Jr.Siba Samal, and Alexander Bukreyev, Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors. Cell Rep.  24(7), 1816-1829, 2018 Aug 14.

Shirvani EPaldurai AManoharan VKVarghese BPSamal SK, A Recombinant Newcastle Disease Virus (NDV) Expressing S Protein of Infectious Bronchitis Virus (IBV) Protects Chickens against IBV and NDV. Sci Rep. 10(8), 2018 Aug 10.

Manoharan VKKhattar SKLaBranche CCMontefiori DCSamal SK,  Modified Newcastle Disease virus as an improved vaccine vector against Simian Immunodeficiency virus. Sci Rep. 8(1), 2018 Jun 12.

Manoharan VKVarghese BPPaldurai ASamal SK. Effect of fusion protein cleavage site sequence on generation of a genotype VII Newcastle disease virus vaccine. PLoS One. 13(5), 2018 May 14.

Yoshida ASamal SK, Avian Paramyxovirus Type-3 as a Vaccine Vector: Identification of a Genome Location for High-Level Expression of a Foreign Gene. Front Microbiol. 8(693), 2017 Apr 20.

Kim SHChen ZYoshida APaldurai AXiao SSamal SK, Evaluation of fusion protein cleavage site sequences of Newcastle disease virus in genotype matched vaccines. PLoS One. 12(3), 2017 Mar 24.

Kim SHPaldurai ASamal SK, A novel chimeric Newcastle disease virus vectored vaccine against highly pathogenic avian influenza virus. Virology. 503:31-36, 2017 Mar.

Awards and Honors

Outstanding Invention of the Year Award, 1990, University of Maryland, College Park

Pfizer Award for Research Excellence, VA-MD College of Veterinary Medicine, 2000

Excellence in Research Award, College of Agriculture and Natural Resources Alumni Association, University of Maryland, College Park, 2007

Dean Gordon Cairns Award for Distinguished Creative Work and Teaching, College of Agriculture and Natural Resources, University of Maryland, College Park, 2007

Faculty Research Award, College of Agriculture and Natural Resources, University of Maryland, College Park, 2013

Fellow of the American Academy of Microbiology, 2014

Distinguished Veterinary Microbiologist of the Year Award 2014, The American College of Veterinary Microbiologists

Phibro Animal Health Excellence in Poultry Research Award, 2015, The American Association of Avian Pathologists

WVPA-Boehringer Ingelheim Innovation in Vaccination Award, 2015, The World Veterinary Poultry Association